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Articles (51)
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1

Ringschlußreaktionen mit N-(Chlormethyl)carbimidoylchloriden, 1. Mitt. Synthesen von Dihydro-1,3,5-triazin-derivaten

Horst Bühme, Hans-Joachim Drechsler

Journal:

Archiv der Pharmazie

Année:

1979

Langue:

german

Fichier:

PDF, 198 KB

german, 1979

2

Postassociation cleaning using linkage disequilibrium information

Buhm Han, Brian M. Hackel, Eleazar Eskin

Journal:

Genetic Epidemiology

Année:

2011

Langue:

english

Fichier:

PDF, 270 KB

english, 2011

3

Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies

Buhm Han, Eleazar Eskin

Journal:

The American Journal of Human Genetics

Année:

2011

Langue:

english

Fichier:

PDF, 668 KB

english, 2011

4

Chromatin marks identify critical cell types for fine mapping complex trait variants

Trynka, Gosia, Sandor, Cynthia, Han, Buhm, Xu, Han, Stranger, Barbara E, Liu, X Shirley, Raychaudhuri, Soumya

Journal:

Nature Genetics

Année:

2012

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2012

5

Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies

J Joo, Jong, Sul, Jae, Han, Buhm, Ye, Chun, Eskin, Eleazar

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 669 KB

english, 2014

6

Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

Han, Buhm, Diogo, Dorothée, Eyre, Steve, Kallberg, Henrik, Zhernakova, Alexandra, Bowes, John, Padyukov, Leonid, Okada, Yukinori, González-Gay, Miguel A., Rantapää-Dahlqvist, Solbritt, Martin, Javier,

Journal:

The American Journal of Human Genetics

Année:

2014

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2014

7

Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes

Okada, Yukinori, Han, Buhm, Tsoi, Lam C., Stuart, Philip E., Ellinghaus, Eva, Tejasvi, Trilokraj, Chandran, Vinod, Pellett, Fawnda, Pollock, Remy, Bowcock, Anne M., Krueger, Gerald G., Weichenthal, Mi

Journal:

The American Journal of Human Genetics

Année:

2014

Langue:

english

Fichier:

PDF, 2.13 MB

english, 2014

8

Variation at HLA-DRB1 is associated with resistance to enteric fever

Dunstan, Sarah J, Hue, Nguyen Thi, Han, Buhm, Li, Zheng, Tram, Trinh Thi Bich, Sim, Kar Seng, Parry, Christopher M, Chinh, Nguyen Tran, Vinh, Ha, Lan, Nguyen Phu Huong, Thieu, Nga Tran Vu, Vinh, Phat

Journal:

Nature Genetics

Année:

2014

Langue:

english

Fichier:

PDF, 626 KB

english, 2014

9

Structural Alignment of Pseudoknotted RNA

Han, Buhm, Dost, Banu, Bafna, Vineet, Zhang, Shaojie

Journal:

Journal of Computational Biology

Année:

2008

Langue:

english

Fichier:

PDF, 594 KB

english, 2008

10

Increasing Power of Groupwise Association Test with Likelihood Ratio Test

Sul, Jae Hoon, Han, Buhm, Eskin, Eleazar

Journal:

Journal of Computational Biology

Année:

2011

Langue:

english

Fichier:

PDF, 499 KB

english, 2011

11

IPED: Inheritance Path-based Pedigree Reconstruction Algorithm Using Genotype Data

He, Dan, Wang, Zhanyong, Han, Buhm, Parida, Laxmi, Eskin, Eleazar

Journal:

Journal of Computational Biology

Année:

2013

Langue:

english

Fichier:

PDF, 277 KB

english, 2013

12

The HLA-DRβ1 amino acid positions 11–13–26 explain the majority of SLE–MHC associations

Kim, Kwangwoo, Bang, So-Young, Lee, Hye-Soon, Okada, Yukinori, Han, Buhm, Saw, Woei-Yuh, Teo, Yik-Ying, Bae, Sang-Cheol

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 919 KB

english, 2014

13

Hap-seq: An Optimal Algorithm for Haplotype Phasing with Imputation Using Sequencing Data

He, Dan, Han, Buhm, Eskin, Eleazar

Journal:

Journal of Computational Biology

Année:

2013

Langue:

english

Fichier:

PDF, 538 KB

english, 2013

14

Association of HLA-DRB1 Haplotypes With Rheumatoid Arthritis Severity, Mortality, and Treatment Response

Viatte, Sebastien, Plant, Darren, Han, Buhm, Fu, Bo, Yarwood, Annie, Thomson, Wendy, Symmons, Deborah P. M., Worthington, Jane, Young, Adam, Hyrich, Kimme L., Morgan, Ann W., Wilson, Anthony G., Isaac

Journal:

JAMA The Journal of the American Medical Association

Année:

2015

Langue:

english

Fichier:

PDF, 498 KB

english, 2015

15

Accurate and Fast Multiple-Testing Correction in eQTL Studies

Sul, Jae Hoon, Raj, Towfique, de Jong, Simone, de Bakker, Paul I.W., Raychaudhuri, Soumya, Ophoff, Roel A., Stranger, Barbara E., Eskin, Eleazar, Han, Buhm

Journal:

The American Journal of Human Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 995 KB

english, 2015

16

Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice

Kang, Eun Yong, Han, Buhm, Furlotte, Nicholas, Joo, Jong Wha J., Shih, Diana, Davis, Richard C., Lusis, Aldons J., Eskin, Eleazar, Gibson, Greg

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2014

17

Effectively Identifying eQTLs from Multiple Tissues by Combining Mixed Model and Meta-analytic Approaches

Sul, Jae Hoon, Han, Buhm, Ye, Chun, Choi, Ted, Eskin, Eleazar, Schork, Nicholas J.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2013

18

Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers

Han, Buhm, Kang, Hyun Min, Eskin, Eleazar, Storey, John D.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 931 KB

english, 2009

19

Interpreting Meta-Analyses of Genome-Wide Association Studies

Han, Buhm, Eskin, Eleazar, Kerr, Kathleen

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 622 KB

english, 2012

20

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

Hu, Xinli, Deutsch, Aaron J, Lenz, Tobias L, Onengut-Gumuscu, Suna, Han, Buhm, Chen, Wei-Min, Howson, Joanna M M, Todd, John A, de Bakker, Paul I W, Rich, Stephen S, Raychaudhuri, Soumya

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2015

21

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

Lenz, Tobias L, Deutsch, Aaron J, Han, Buhm, Hu, Xinli, Okada, Yukinori, Eyre, Stephen, Knapp, Michael, Zhernakova, Alexandra, Huizinga, Tom W J, Abecasis, Gonçalo, Becker, Jessica, Boeckxstaens, Guy

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2015

22

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Ellinghaus, David, Jostins, Luke, Spain, Sarah L, Cortes, Adrian, Bethune, Jörn, Han, Buhm, Park, Yu Rang, Raychaudhuri, Soumya, Pouget, Jennie G, Hübenthal, Matthias, Folseraas, Trine, Wang, Yunpeng,

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2016

23

A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping

Han, Buhm, Duong, Dat, Sul, Jae Hoon, de Bakker, Paul I. W., Eskin, Eleazar, Raychaudhuri, Soumya

Journal:

Human Molecular Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 313 KB

english, 2016

24

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

Han, Buhm, Pouget, Jennie G, Slowikowski, Kamil, Stahl, Eli, Lee, Cue Hyunkyu, Diogo, Dorothee, Hu, Xinli, Park, Yu Rang, Kim, Eunji, Gregersen, Peter K, Dahlqvist, Solbritt Rantapää, Worthington, Jan

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2016

25

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

Trynka, Gosia, Westra, Harm-Jan, Slowikowski, Kamil, Hu, Xinli, Xu, Han, Stranger, Barbara E., Klein, Robert J., Han, Buhm, Raychaudhuri, Soumya

Journal:

The American Journal of Human Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2015

26

Multiple testing correction in linear mixed models

Joo, Jong Wha J., Hormozdiari, Farhad, Han, Buhm, Eskin, Eleazar

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2016

27

Imputing Phenotypes for Genome-wide Association Studies

Hormozdiari, Farhad, Kang, Eun Yong, Bilow, Michael, Ben-David, Eyal, Vulpe, Chris, McLachlan, Stela, Lusis, Aldons J., Han, Buhm, Eskin, Eleazar

Journal:

The American Journal of Human Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 562 KB

english, 2016

28

A Modeling Study on Hypoxia Formation in the Bottom Water of the Youngsan River Estuary, Korea

Cho, Chang-Woo, Song, Yong-Sik, Kim, Choong-Ki, Kim, Tae-In, Han, Jong-Su, Woo, Seong-Buhm, An, Soonmo, Choi, Taejun

Journal:

Journal of Coastal Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2015

29

Using genomic annotations increases statistical power to detect eGenes

Duong, Dat, Zou, Jennifer, Hormozdiari, Farhad, Sul, Jae Hoon, Ernst, Jason, Han, Buhm, Eskin, Eleazar

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 457 KB

english, 2016

30

X Chromosome-wide Association Study Identifies a Susceptibility Locus for Inflammatory Bowel Disease in Koreans

Lee, Ho-Su, Oh, Hyunjung, Yang, Suk-Kyun, Baek, Jiwon, Jung, Seulgi, Hong, Myunghee, Kim, Kyung Mo, Shin, Hyoung Doo, Kim, Kyung-Jo, Park, Sang Hyoung, Ye, Byong Duk, Han, Buhm, Song, Kyuyoung

Journal:

Journal of Crohn's and Colitis

Année:

2017

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2017

31

Association of CDKN2A/B with inflammatory bowel disease in Koreans

Lee, Ho-Su, Lee, Soo Bin, Kim, Byoung Mok, Hong, Myunghee, Jung, Seulgi, Hong, Jeonghoon, Baek, Jiwon, Han, Buhm, Oh, Seak Hee, Kim, Kyung Mo, Park, Sang Hyoung, Yang, Suk-Kyun, Ye, Byong Duk, Song, K

Journal:

Journal of Gastroenterology and Hepatology

Année:

2017

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2017

32

FOLD: a method to optimize power in meta-analysis of genetic association studies with overlapping subjects

Kim, Emma E, Lee, Seunghoon, Lee, Cue Hyunkyu, Oh, Hyunjung, Song, Kyuyoung, Han, Buhm

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 589 KB

english, 2017

33

Encyclopedia of Life Sciences || Multiple Testing in Genetic Epidemiology

Année:

2001

Langue:

english

Fichier:

PDF, 262 KB

english, 2001

34

Applying meta-analysis to genotype-tissue expression data from multiple tissues to identify eQTLs and increase the number of eGenes

Duong, Dat, Gai, Lisa, Snir, Sagi, Kang, Eun Yong, Han, Buhm, Sul, Jae Hoon, Eskin, Eleazar

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 422 KB

english, 2017

35

Immunochip meta-analysis of inflammatory bowel disease identifies three novel loci and four novel associations in previously reported loci

Hong, Myunghee, Ye, Byong Duk, Yang, Suk-Kyun, Jung, Seulgi, Lee, Ho-Su, Kim, Byoung Mok, Lee, Soo Bin, Hong, Jeonghoon, Baek, Jiwon, Park, Sang Hyoung, Han, Buhm, Li, Yi, Liu, Wenting, Haritunians, T

Journal:

Journal of Crohn's and Colitis

Année:

2018

Langue:

english

Fichier:

PDF, 974 KB

english, 2018

36

An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures

Kang, Eun Yong, Lee, Cue Hyunkyu, Furlotte, Nicholas A., Joo, Jong Wha J., Kostem, Emrah, Zaitlen, Noah, Eskin, Eleazar, Han, Buhm

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2018

37

Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

Jia, Xiaoming, Han, Buhm, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick J., Rich, Stephen S., Raychaudhuri, Soumya, de Bakker, Paul I.W., Tang, Jianming

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2013

38

Amino acid position 37 of HLA-DRβ1 affects susceptibility to Crohn’s disease in Asians

Han, Buhm, Akiyama, Masato, Kim, Kyung-Kon, Oh, Hyunjung, Choi, Hyunchul, Lee, Cue Hyunkyu, Jung, Seulgi, Lee, Ho-Su, Kim, Emma E, Cook, Seungho, Haritunians, Talin, Yamazaki, Keiko, Park, Sang Hyoung

Journal:

Human Molecular Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2018

39

ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis

Kang, Eun Yong, Park, Yurang, Li, Xiao, Segrè, Ayellet V., Han, Buhm, Eskin, Eleazar

Journal:

G3 Genes|Genome|Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 918 KB

english, 2016

40

Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-Scores

Lee, Cue Hyunkyu, Cook, Seungho, Lee, Ji Sung, Han, Buhm

Journal:

Genomics & Informatics

Année:

2016

Langue:

english

Fichier:

PDF, 469 KB

english, 2016

41

Effects of smoking on the association of HLA with ulcerative colitis

Lee, Ho‐Su, Kim, Kihyun, Jung, Seulgi, Hong, Myunghee, Kim, Byoung Mok, Yoo, Dae‐sung, Moon, Jung Won, Baek, Jiwon, Hwang, Sung Wook, Park, Sang Hyoung, Yang, Suk‐Kyun, Han, Buhm, Song, Kyuyoung, Ye,

Journal:

Journal of Gastroenterology and Hepatology

Année:

2019

Langue:

english

Fichier:

PDF, 514 KB

english, 2019

42

Effects of smoking on the association of HLA with ulcerative colitis

Lee, Ho‐Su, Kim, Kihyun, Jung, Seulgi, Hong, Myunghee, Kim, Byoung Mok, Yoo, Dae‐sung, Moon, Jung Won, Baek, Jiwon, Hwang, Sung Wook, Park, Sang Hyoung, Yang, Suk‐Kyun, Han, Buhm, Song, Kyuyoung, Ye,

Journal:

Journal of Gastroenterology and Hepatology

Année:

2019

Fichier:

PDF, 514 KB

2019

43

Prognostic value of the association between MHC class I downregulation and PD-L1 upregulation in head and neck squamous cell carcinoma patients

Yoo, Shin Hye, Keam, Bhumsuk, Ock, Chan-Young, Kim, Sehui, Han, Buhm, Kim, Ji-Won, Lee, Keun-Wook, Jeon, Yoon Kyung, Jung, Kyeong Cheon, Chung, Eun-Jae, Kwon, Seong Keun, Ahn, Soon-Hyun, Sung, Myung-W

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2019

44

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

Pouget, Jennie G, Han, Buhm, Wu, Yang, Mignot, Emmanuel, Ollila, Hanna M, Barker, Jonathan, Spain, Sarah, Dand, Nick, Trembath, Richard, Martin, Javier, Mayes, Maureen D, Bossini-Castillo, Lara, López

Journal:

Human Molecular Genetics

Année:

2019

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2019

45

Clinically Applicable Deep Learning Algorithm Using Quantitative Proteomic Data

Kim, Hyunsoo, Kim, Yoseop, Han, Buhm, Jang, Jin-Young, Kim, Youngsoo

Journal:

Journal of Proteome Research

Année:

2019

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2019

46

Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancer

Kim, Dong Ha, Kim, HyeongRyul, Choi, Yun Jung, Kim, Seon Ye, Lee, Jung-Eun, Sung, Ki Jung, Sung, Young Hoon, Pack, Chan-Gi, Jung, Min-kyo, Han, Buhm, Kim, Kunhee, Kim, Woo Sung, Nam, Soo Jeong, Choi,

Journal:

Experimental and Molecular Medicine

Année:

2019

Langue:

english

Fichier:

PDF, 2.13 MB

english, 2019

47

Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature

Jung, Jaeyun, Lee, Cue Hyunkyu, Seol, Hyang Sook, Choi, Yeon Sook, Kim, Eunji, Lee, Eun Ji, Rhee, Je-Keun, Singh, Shree Ram, Jun, Eun Sung, Han, Buhm, Hong, Seung Mo, Kim, Song Cheol, Chang, Suhwan

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.89 MB

english, 2016

48

Genomic GPS: using genetic distance from individuals to public data for genomic analysis without disclosing personal genomes

Kim, Kunhee, Baik, Hyungryul, Jang, Chloe Soohyun, Roh, Jin Kyung, Eskin, Eleazer, Han, Buhm

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2019

49

Expression Quantitative Trait Loci (eQTL) Mapping in Korean Patients With Crohnâs Disease and Identification of Potential Causal Genes Through Integration With Disease Associations

Jung, Seulgi, Liu, Wenting, Baek, Jiwon, Moon, Jung Won, Ye, Byong Duk, Lee, Ho-Su, Park, Sang Hyoung, Yang, Suk-Kyun, Han, Buhm, Liu, Jianjun, Song, Kyuyoung

Journal:

Frontiers in Genetics

Année:

2020

Fichier:

PDF, 791 KB

2020

50

Genetic stratification of depression in UK Biobank

Howard, David M., Folkersen, Lasse, Coleman, Jonathan R. I., Adams, Mark J., Glanville, Kylie, Werge, Thomas, Hagenaars, Saskia P., Han, Buhm, Porteous, David, Campbell, Archie, Clarke, Toni-Kim, Bree

Journal:

Translational Psychiatry

Année:

2020

Fichier:

PDF, 798 KB

2020